Analysis Note

ControlPOSITIVE CONTROL: HeLa cells colon carcinoma

Application

Anti-p16 Antibody, clone D25 is a Mouse Monoclonal Antibody for detection of p16 also known as INK4a, MTS1, CDK4IN, CDKN2 & has been validated in WB & IHC.

Research CategoryEpigenetics & Nuclear Function

Immunoblotting

Immunohistochemistry

Optimal working dilutions must be determined by end user.

Research Sub CategoryCell Cycle, DNA Replication & Repair

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Recombinant p16 fusion protein from E. coli.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 04-239

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Liquid in phosphate buffer, containing azide as a preservative.

Format: Purified

Specificity

P16* is a major tumor suppressor gene, which is known to be deleted or mutated in many types of human cancers. Antibody MAB4133 binds specifically to p16 in its recombinant or native form. It also recognizes p16 expressed by melanomas and neve in situ.

Storage and Stability

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.